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glk glucokinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946858, updated on 19-Sep-2024

Summary

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Official Symbol
glk
Official Full Name
glucokinase
Primary source
ECOCYC:EG12957
Locus tag
b2388
See related
ASAP:ABE-0007875
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2384
Summary
The cytoplasmic glucokinase is not required for growth on glucose as the carbon source, because glucose is phosphorylated during transport by the PTS system. [More information is available at EcoCyc: EG12957].
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Genomic context

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Sequence:
NC_000913.3 (2508461..2509426, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative PTS enzyme IIC component FryC Neighboring gene putative PTS enzyme IIB component FryB Neighboring gene putative transport protein YfeO Neighboring gene DUF2502 domain-containing protein YpeC

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables D-glucose binding IEA
Inferred from Electronic Annotation
more info
  
enables glucokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucokinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glucokinase activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glucose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within glycolytic process EXP
Inferred from Experiment
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
glucokinase
NP_416889.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2508461..2509426 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416889.1 glucokinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416889.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S0FPW9
    Conserved Domains (1) summary
    PRK00292
    Location:2 → 316
    glk; glucokinase; Provisional
Nucleotide Protein
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